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This revised, expanded second edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genomewide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.
ISBN: 9783319562087
Auflage: 2
Sprache: Englisch
Seitenzahl: 431
Produktart: Gebunden
Herausgeber: Meschia, James F. Sharma, Pankaj
Verlag: Springer International Publishing
Veröffentlicht: 26.06.2017
Schlagworte: CADASIL Fabry GWAS MELAS cerebral hemorrhage genetics genome hypertension stem cell stroke
Pankaj Sharma, MD, PhD, FRCPReader & Consultant NeurologistImperial College London & Hammersmith HospitalsLondon, UKJames F. Meschia, MDChair, Department of NeurologyMayo ClinicJacksonville, Florida, USA

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