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In his master thesis Thorsten Will proposes the substantial information content of protein complexes involving transcription factors in the context of gene regulatory networks, designs the first computational approaches to predict such complexes as well as their regulatory function and verifies the practicability using data of the well-studied yeast S.cereviseae. The novel insights offer extensive capabilities towards a better understanding of the combinatorial control driving transcriptional regulation.
Autor: Will, Thorsten
ISBN: 9783658082680
Sprache: Englisch
Seitenzahl: 142
Produktart: Kartoniert / Broschiert
Verlag: Springer Fachmedien Wiesbaden GmbH
Veröffentlicht: 18.12.2014
Untertitel: A Novel Approach to Data Integration in Systems Biology
Schlagworte: Bioinformatics Gene Regulatory Networks Graph Algorithms Protein Complexes Transcriptional Regulation
Currently, the author is pursuing his Ph.D. at the Center for Bioinformatics in Saarbrücken, Germany.