Zum Hauptinhalt springen Zur Suche springen Zur Hauptnavigation springen
Herzlich Willkommen!
Phosphatases, such as TNAP are fundamental in regulating the roles of cellular, and consequently numerous body functions. TNAP is a ubiquitous enzyme with a wide spectrum of substrates and specificity. Regulation at the cellular level and the lack of TNAP activity is a lethal condition. Recent findings of a highly specific regional, laminar and subcellular localization of TNAP in the cerebral cortex indicates that in addition to its metabolic and skeletal functions, TNAP also plays a role in regulating cerebral functions, most probably cognition. In fact, TNAP disturbance could result in complex diseases such as epilepsy, developmental retardation and Alzheimer's disease. Available data suggest that, regarding brain functions, TNAP is a potentially important target of clinical research. This book aims to provide an overview of our current understanding of the functions of TNAP in the brain and on other tissues and organs.
ISBN: 9789401771962
Sprache: Englisch
Seitenzahl: 395
Produktart: Gebunden
Herausgeber: Fonta, Caroline Négyessy, László
Verlag: Springer Netherland
Veröffentlicht: 07.08.2015
Schlagworte: Brain development Cerebral cortex Epilepsy Metabolic disorders Neurobiology

Das könnte Sie auch interessieren

Verwandte Artikel