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This book is indispensable to researchers in fields as diverse as molecular biology and biophysics. It is an essential text for university libraries, covering as it does the important role that mitochondria play in a variety of biochemical spheres. The work has been co-authored by two leading figures in the field of biomedical research. In it, they analyse how mitochondria affect metabolic pathways, how they are active in the regulation of cytosolic constituents, and their role in initiating signal pathways. Also covered are the way mitochondria help to regulate apoptosis, and how they modulate cellular hypertrophy and proliferation. It gives an overview of the emergence of mitochondria as an important regulator of cell signaling, with a particular focus on their pathophysiology.
ISBN: 9780387699448
Sprache: Englisch
Seitenzahl: 359
Produktart: Gebunden
Herausgeber: Schaffer, Stephen W. Suleiman, M. Saadeh
Verlag: Springer US
Veröffentlicht: 22.08.2007
Untertitel: The Dynamic Organelle
Schlagworte: Amino acid Calcium DNA Oxidation Peroxisom amino acids metabolism molecular biology physiology regulation
Dr. Stephen W. Schaffer is a professor at the University of South Alabama. He is a member of the editorial board of Molecular and Cellular Biochemistry.Dr. M.-Saadeh Suleiman is a professor at the University of Bristol, UK. His research includes investigating the role of metabolites and ionic species in myocardial protection, with special emphasis on amino acids, mitochondria, Ca2+ loading and reactive oxygen species.

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