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This volume provides the most recent developments and methodologies on metastatic process, formation, and detection.  Chapters guide readers through functional metastasis in vitro assays, non-mouse and mice metastasis models, methods for imaging metastasis, analyzing the tumor microenvironment, senescence and inflammation with respect to metastasis, methods to investgate the premetastatic/ metastatic, detecting biomarkers in patient, and bioinformatics to simulate the metastatic process. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.   Authoritative and cutting-edge,  Metastasis: Methods and Protocols aims to be a useful practical guide to researches to help further their study in this field.
ISBN: 9781071613528
Sprache: Englisch
Seitenzahl: 348
Produktart: Kartoniert / Broschiert
Herausgeber: Stein, Ulrike S.
Verlag: Springer US
Veröffentlicht: 20.03.2022
Untertitel: Methods and Protocols
Schlagworte: NCI60 tumor cell PET/MRI PET/MRI carcinoma metastasis senescence- associated secretory phenotype (SASP) xenografted mouse models

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