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This book highlights the impact of nutrients on early placentation processes and their relevance for fetal growth and pregnancy outcome. The role of maternal nutrition on fetal growth and development has been evidenced in many epidemiological studies that included infamous Dutch famine, Helsinki Birth cohort and others. Fetal programming hypothesis states that the nutritional and other environmental conditions under which an individual develops from pre-conception to birth has a major impact on the future health of the newborn child. The developmental environment of the fetus is primarily dependent on two major factors that are maternal nutritional state (excess/low/imbalance) and placental function. Placentation is characterized by the extensive remodeling of the maternal uterine vasculature producing low-resistance blood vessels that facilitate the exchange of nutrients and wastes between the mother and the fetus. Cellular and molecular mechanisms involved in human placental blood vessel formation, which are now well established, are discussed.
Autor: Basak, Sanjay Duttaroy, Asim K.
ISBN: 9783319817507
Sprache: Englisch
Seitenzahl: 159
Produktart: Kartoniert / Broschiert
Verlag: Springer International Publishing
Veröffentlicht: 07.06.2018
Untertitel: Effects on First Trimester Placenta
Schlagworte: Angiogenic signaling Blastocyst Early pregnancy Feto-placental unit Folic acid Intrauterine growth Nutrition Placentation Preeclampsia Trophoblast
Asim K. Duttaroy is Professor in the Division of Clinical Nutrition at the University of Oslo, Norway. Sanjay Basak, PhD, works in the Molecular Biology Division of the National Institute of Nutrition (ICMR), Hyderabad, India.

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