Zum Hauptinhalt springen Zur Suche springen Zur Hauptnavigation springen
Herzlich Willkommen!
The work described in this book is an excellent example of interdisciplinary research in systems biology. It shows how concepts and approaches from the field of physics can be efficiently used to answer biological questions and reports on a novel methodology involving creative computer-based analyses of high-throughput biological data. Many of the findings described in the book, which are the result of collaborations between the author (a theoretical scientist) and experimental biologists and between different laboratories, have been published in high-quality peer-reviewed journals such as Molecular Cell and Nature. However, while those publications address different aspects of post-transcriptional gene regulation, this book provides readers with a complete, coherent and logical view of the research project as a whole. The introduction presents post-transcriptional gene regulation from a distinct angle, highlighting aspects of information theory and evolution and laying the groundwork for the questions addressed in the subsequent chapters, which concern the regulation of the transcriptome as the primary functional carrier of active genetic information.
Autor: Jens, Marvin
ISBN: 9783319070810
Sprache: Englisch
Seitenzahl: 99
Produktart: Gebunden
Verlag: Springer International Publishing
Veröffentlicht: 05.06.2014
Untertitel: Combining Computation and High-throughput Experiments in Systems Biology
Schlagworte: Binding site occupancy CDR1as Competing RNA ELAVL1 HuR Model of ELAVL1 binding PAR-CLIP clusters and filtering PAR-CLIP computational pipeline Post-transcriptional regulation RNA-binding proteins RNA competition theory

Das könnte Sie auch interessieren

Verwandte Artikel